Funded under the National Recovery and Resilience Plan (NRRP), Mission 4 Component 2 Investment 1.3, Theme 10.
Identify the factors influencing adherence to the Mediterranean diet with attention to children and adolescents in Italy (including consumer needs and preferences, local determinants/drivers of food choices in connection with Spoke 1).
Inclusion of a subgroup of participants for data collection at in-patient clinics, including biological samples at various time points and matching with nutritional data (24-h recalls) to identify biomarkers of consumption and related markers (M24)
Cardio-metabolic risk factors affect to the highest of proportion of the global burden of diseases, being responsible for a large share of deaths from cardiovascular and metabolic diseases. Obesity is considered the largest pandemic affecting people globally in both developed and developing countries, including those living in the Mediterranean region. Together with type-2 diabetes mellitus, elevated blood pressure, and dyslipidemia, the burden of cardio-metabolic disorders represents a public health issue for the general population due to their impact in also affecting the morbidity and quality of life of the general population.
Data on background characteristics, dietary habits, time of eating, and sleep quality will be collected in patients at high cardiovascular risk attending in-patient clinics. Biological specimens will be collected to be matched with food frequency questionnaire data and further analyzed for identification of biomarkers of dietary consumption and patterns of food intake, with focus on the Mediterranean diet, as well as biomarkers of disease gravity and predictors of outcome.
The association between dietary factors and disease parameters and progression will be investigated.