WP 6.2Spoke 06

Reduce malnutrition: strategies in a sustainable framework

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Highlights

Research projects
Outputs
Work Package 6.2 will present a sustainable, tailored, multidimensional approach to reducing malnutrition by exploiting the interactions between environment, food, genotype, and phenotype within specific population groups. 

As part of this work, it is also expected an analysis of the positive and negative interactions between lifestyle, socioeconomic status, clinical condition, psychological distress, medical treatment, and diet for the implementation of sustainable dietary patterns; a validation of biomarker malnutrition and a draft of sustainable nutritional protocols, in relation with Spoke 1 and 4.

The next task that will be carried out jointly with Spoke 2, 3 and 4 is centred on developing and applying in vitroin vivo, and in silico experimental models to understand better the mechanisms of action in counteracting malnutrition of new sustainable bioactive molecules from different matrices.

The final task of Work Package 6.2 relies on designing a user-friendly, personalised web tool for monitoring and fostering remotely sustainable, target-specific food behaviours. The application's responsiveness features will be available on various devices like PCs and smartphones.

Task and deliverables

Task 6.2.1.

Identification of sustainable tailored multidimensional approach including nutritional strategies aimed at reducing malnutrition in target specific populations by exploiting the interactions between environment, food, genotype and phenotype: a) analysis of the positive and negative interactions between lifestyle, socioeconomic status, clinical condition, psychological distress, medical treatment and diet for the implementation of sustainable dietary patterns; b) malnutrition biomarker validation; c) draft of sustainable nutritional protocols (in connection with Spoke 1 and 4).

Task 6.2.2.

Development and application of in vitro, in vivo and in silico experimental models for the understanding of the mechanism of action in counteracting malnutrition of new sustainable bioactive molecules from different matrices (in connection with Spoke 2, 3 and 4).

Task 6.2.3.

Design of a friendly end user personalised web responsive application for remote promoting and monitoring of sustainable target specific dietary patterns. The responsiveness features of the application will be made available on different devices (e.g., PC, smartphone)

Milestones

M6.2.1.1.

List of nutrition protocols and existing biomarkers for specific target groups with malnutrition that would benefit improvement (M12)

M6.2.2.1.

List of new sustainable bioactive molecules proven to directly impact nutritional status in specific target groups with malnutrition (M18)

M6.2.3.1.

Identification and computerization of existing Clinical Practice Guidelines addressing malnutrition (M8)

M6.2.3.2.

Development of an engine for assessing dietary regimens based on their observed efficacy on the target patients (M18).