Research project
30 | monthsINIAS_BIOREFUND

Targeted and untargeted approaches for the determination of both intentionally and non-intentionally added substances from bio-based, recycled and functional food contact materials

Related toSpoke 03

Principal investigators
Maria Careri

Other partecipants Federica Bianchi, Antonella Cavazza, Monica Mattarozzi, Nicolò Riboni, Maurizio Piergiovanni
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Highlights

Project partners

Barilla

Partner

Task involved

Task 3.1.3.

New/existing materials will be characterised in terms of migration studies of both intentionally and non-intentionally added substances, small-/micro/nano- plastics, metal nanoparticles, food packaging suitability and growth of mycotoxigenic moulds, even after being subjected to innovative/emerging processing technologies (e.g., cold gas plasma, HPP). Potential antimicrobial properties will also be assessed, particularly for developed functional packaging systems. The safety of new materials used as FCM, from recyclable sources, bioplastics or derived from by-products, will be assessed in collaboration with Spoke 2

Project deliverables

D3.1.3.1.

Report on safety / stability functionality of new/existing food packaging materials/systems (M30)

D3.1.3.3.

Report on added substances, small nano-plastics, metal nanoparticles (M30)

Interaction with other spokes

State of the art

The safety of existing/new food contact materials (FCM) is an issue of major concern since many harmful compounds resulting from manufacturing processes, recycling technologies or material aging can migrate into food, raising health concerns. Mass spectrometry (MS)-based techniques can be applied for the determination of both intentionally and non-intentionally added substances both from extracts and directly from the packaging material, being high resolution-MS (HRMS) the most powerful tool for the unambiguous determination of the investigated analytes. Untargeted strategies play a key role in the assessment of food safety being able to provide a comprehensive fingerprinting of FCM. Ambient HRMS provides the direct molecular characterization of FCM with minimal sample preparation, whereas MS imaging approaches enable mapping of the spatial distribution of components on sample surfaces, leading to a better understanding of the localization of packaging components for an improved product safety.

Operation plan

  • Selection of commercially available bio-based, recycled and functional food contact materials for food products.
  • Selection of newly developed functional food contact materials for food products. 
  • Development and validation of innovative liquid chromatography-HRMS methods for the targeted and untargeted determination of both intentionally and non-intentionally added substances.  
  • Development and validation of gas chromatography-MS methods for the targeted and untargeted determination of both intentionally and non-intentionally added substances.
  • Development and validation of ambient-HRMS for the rapid screening of harmful compounds directly released from existing and newly developed food contact materials.

Expected results

  • Highly sensitive liquid chromatography-HRMS methods for the targeted and untargeted determination of both intentionally and non-intentionally added substances in commercially available and newly developed bio-based, recycled and functional food contact materials.
  • Reliable gas chromatography-MS methods for the targeted and untargeted determination of both intentionally and non-intentionally added volatile substances in commercially available and newly developed bio-based, recycled and functional food contact materials.
  • Rapid and high-throughput desorption ionization-HRMS methods for screening the presence of harmful compounds in existing and newly developed food contact materials.
    Identification of the most suitable packaging solutions for selected food applications.